Animal and Translational Models for CNS Drug Discovery: Psychiatric Disorders
The use of appropriate models can minimize the number of drug candidates that later fail in human trials by accurately predicting the efficacy and the toxicity of each compound. This can be improved with more informed selection of the appropriate models. This book provides disorder-specific guidelines to selecting the appropriate non-human models for trials in the drug discovery and development process. "Psychiatric Diseases" is written for researchers in both academia and the pharmaceutical industry who use animal models in research and development of drugs for psychiatric disorders such as anxiety, depression, and schizophrenia. This is the first volume in the three volume-set, "Animal and Translational Models for CNS Drug Discovery" 978-0-12-373861-5 , and is also available for purchase individually.
This title includes: case studies of real-life trials that resulted in moving to the human trials phases; details for each disorder on how to analyze and determine what the results mean to the overall drug discovery/development process; and, discussion of the clinical presentation of each psychiatric disorder and the issues surrounding the design and conductuance of clinical trials of potential drugs for treatment.