Tumors of the Central Nervous System, Volume 1
The most recent developments in diagnostic and therapeutic aspects of Gliomas (Glioblastoma) in the brain are presented. The importance of personalized medicine and clinical validation for targeted therapy are discussed. The identification of various types of biomarkers is included. The identification and validation of brain cancer (glioblastoma) genes are discussed. Role of cancer stem cells in the initiation, progression, and persistence of malignant gliomas is explained. The use of surgical resection, chemotherapy (e.g., temozolomide), immunotherapy, and radiotherapy for malignant glioblastoma are pointed out. Standard (established) as well as newer imaging modalities (proton magnetic resonance spectroscopy) are discussed.
Targeted therapy determined by molecular genetics is emphasizedRole of molecular genetics in the CNS cancer development is discussedAdvantages and limitations of biomarkers in tumor detection and diagnosis are detailedThe role of translational medicine is emphasized (bench to bed)Can be used as an outside reading to obtain additional information at seminars and conferences in the medical fieldTeachers in medicine would be interested