Physical Activity, Dietary Calorie Restriction, and Cancer
The World Health Organization estimates that 25 percent of common cancers can be prevented through regular physical activity and weight control. Common cancers linked to overweight/obesity and a sedentary lifestyle include breast, colon, endometrium, pancreas, renal, esophageal, and several others. There are several plausible mechanisms linking lack of physical activity and increased adiposity to cancer risk, supported by results from animal experiments and human intervention studies.
This volume will provide overviews of the epidemiology of physical activity, obesity and cancer. It will review the animal model data on dietary calorie restriction, exercise, and carcinogenesis. It will present the human intervention studies that have tested exercise or dietary-induced weight loss on cancer biomarkers. It will also review the studies of physical activity, weight control, and prognosis in individuals with cancer.