Hereditary Colorectal Cancer
Colorectal cancer is the third most commonly diagnosed cancer in the US and the third most recently linked to cancer deaths. The national annual incidence rate of colorectal cancer is approximately 148,000+, striking slightly more females than males. The lifetime risk of colorectal cancer is 5-6%, however patients with a familial risk (with two or more first or second degree relatives) make up 20% of the patients. Persons who carry genetic mutations linked to hereditary colorectal cancer are the most likely to develop the disease.
Hereditary nonpolyposis colorectal cancer (HNPCC), also known as the Lynch syndrome, has not yet been covered in one comprehensive textThe basic and clinical knowledge related to hereditary colorectal cancer is expanding and evolving rapidlyA panel of worldwide experts address the issues surrounding hereditary colorectal cancer