Transactions on Computational Systems Biology V
This issue of Transactions on Computational Systems Biology contains a sel- tion of papers presented initially at the 2005 IEEE International Conference on Granular Computing held in Beijing, July 25–27, and a few invited papers. - persincludedinthisspecialissuearedevotedtovariousaspectsofcomputational methods, algorithms, and techniques in bioinformatics such as gene expression analysis, biomedical literature mining and natural language processing, protein structure prediction, biological database management and biomedical infor- tion retrieval. Z. Huang, Y. Li and X. Hu present a novel SVM-based method to predict anti-parallel structure from sequence data. C.H. Liu, I.-J. Chiang, J.-M. Wong, H.-C. Tsai and T.Y. Lin introduce a novel model of concept representation called Latent Semantic Networks using a multilevel geometric structure. B. Jin and Y.-Q. Zhang propose a new system to evolve the structures of granular kernel trees (GKTs) in the case that we lack knowledge to prede?ne kernel trees. The new granular kernel tree structure evolving system is used for cyclooxygenase-2 inhibitor activity comparison. M.K. Ng, S.-Q. Zhang, W.-K. Ching and T. Akutsu study a control model for gene intervention in a genetic regulatory network. At each time step, a ?nite number of controls are allowed to drive to some target states (i.e., some speci?c genes are on, and some speci?c genes are o?) of a genetic network.
Collects carefully chosen and enhanced contributions initially presented at the 2005 IEEE International Conference on Granular Computing, Beijing, July 2005Presents 9 papers devoted to various aspects of computational methods, algorithms and techniques in bioinformaticsCoverage includes gene expression analysis, biomedical literature mining and natural language processing, protein structure prediction, biological database management and biomedical information retrieval