100 Years of Schizophrenia
Special Topic Issue: Neuropsychobiology 2012, Vol. 66, No. 1
The articles in this issue are based on a symposium that was held in Marburg to celebrate the 100th anniversary of the publication of Eugen Bleuler’s monograph on schizophrenia. They discuss all aspects of schizophrenia in the light of data from current research and review current hypotheses of neurobiological correlates of delusions, hallucinations and ego disturbances. In addition, topics such as reelin expression in the cortex, neural activation during reward processing in subjects with an ultra-high risk for schizophrenia, brain structural variations in patients and imaging endophenotypes are discussed. Included are also a number of comprehensive reviews on early-onset schizophrenia and psychosocial interventions. It concludes with a presentation of Eugen Bleuler’s concept of schizophrenia and its relevance to present-day psychiatry.
This issue will provide valuable reading for all researchers and clinicians in fields such as psychiatry and psychology as well as for psychotherapists and neurologists.