Commercially, D-xylitol is produced by chemical reactions that are tailored to the requirements of various sectors. However, due to the rising interest in sustainable development and ecologically benign practices, microbial transformation processes are generally preferred over the conventional chemical conversion process. The former have multiple advantages, including less chemical load on the environment, higher efficiency, and the ability to dilute multiple downstream transformation attempts while maintaining product yield and recovery.
This book aims to disseminate the most current advances in the biotechnological production of D-xylitol and its applications in medical and health care. It is a unique collection of 15 book chapters split into 5 sections and written by experts in their respective fields, who present critical insights into several topics, review current research, and discuss future progress in this area. This book also provides essential information on hemicellulose hydrolysis to recover D-xylose, detoxification of hemicellulose hydrolysates, and improved fermentation methods for increased D-xylitol production. The highlights of strain improvement to increase the D-xylitol titers and downstream recovery of D-xylitol are also discussed in several sections. The current applications of D-xylitol in medical and health care have been used to justify the cost incurred for setting up the demonstration plant for D-xylitol production in the market. Apart from researchers and post-graduate students in the field of microbial biotechnology, this book will assist those in the business community who deal with the economic analysis of bio-based products and their marketing.
A unique collection of chapters which present the latest research progress of biotechnological production of D-xylitol from renewable resources, the application range of xylitol and the challenges in large scale production operationsPresents clear concepts of plant cell wall degradation, separation of biomolecules, kinetics of D-xylitol production with mass balance, metabolic engineering of xylitol synthesis in microorganisms and downstream processing for xylitol recoveryThe book discusses the medical applications of D-xylose (diabetic patients, odontological, lipid metabolism disorders, renal and parenteral lesions, otitis media, lung infections, antimicrobial and anti-adherence activities, and osteoporosis) thus making it unique to graduate students and researchers in the medical community